What is a vampire facelift?

by Ruben Mislang | May 24, 2020 | Uncategorized

Research: when given time and educational materials to debate whether or not to proceed with hip replacement, patients find it easier to say no to hip replacement.

A team of European researchers lead by Espen Andreas Brembo of the University College of Southeast Norway, published a study in the medical journal BMC Health Services Research to support the idea that patients should not be shuttled into hip replacement without giving them the education materials necessary to help them make an informed choice about hip osteoarthritis treatments. This includes whether or not they can realistically avoid a hip replacement:

A combined research team from the Universities of Montreal, Ottawa, Toronto, and Chicago concluded that: when given time and educational materials to debate whether or not to proceed with hip replacement, patients decided on having less surgeries.(1) Research such as this makes clear that people with hip osteoarthritis are too often told only about hip replacement.

What is the information that changes people’s minds about surgery?

People have an expectation that hip replacement surgery fixes everything and improves general overall health. People have an expectation that insurance will cover everything making hip replacement affordable and available to them. There is a lot of expectation. Research that we will see below says these expectations are not met, and this is clearly cause for concern.

Research: Many people who had hip replacement required 12 weeks to get back to work. “A considerable proportion of the patients returning to work worked less hours than preoperatively.”

• Research published in the health journal PLusOne suggests that doctors may have interpreted patient results as being much better than they actually were to support the use of a specific implant or specific technique?(2)
• Research: A study from the United Kingdom in The Journal of bone and joint surgery reported on patients who had between 1 and 15 revision operations after their primary joint replacement. They found that these patients spent great amounts of time immobilized between and waiting on their next surgery and that this caused further health problems.(3)
• Research: Japanese doctors  examined the fall risk in patients following hip replacement. They found an increased risk for falls and fall-induced injuries mostly associated with medication.(4)
• Research: Doctors found that there are no clear answers in preventing dislocation of the new hip joint. The cause of dislocation are many.(5)
• Research: Many people who had hip replacement required 12 weeks to get back to work. “A considerable proportion of the patients returning to work worked less hours than preoperatively.” More research into patients who do not return or decrease their working hours is needed.(6)

1 Brembo EA, Kapstad H, Eide T, Månsson L, Van Dulmen S, Eide H. Patient information and emotional needs across the hip osteoarthritis continuum: a qualitative study. BMC Health Services Research. 2016;16:88. doi:10.1186/s12913-016-1342-5.
2 Tsertsvadze A, Grove A, Freeman K, et al. Total Hip Replacement for the Treatment of End Stage Arthritis of the Hip: A Systematic Review and Meta-Analysis. Zintzaras E, ed. PLoS ONE. 2014;9(7):e99804. doi:10.1371/journal.pone.0099804.
3 Judge A, Arden NK, Price A, Glyn-Jones S, Beard D, Carr AJ, Dawson J, Fitzpatrick R, Field RE. Assessing patients for joint replacement: can pre-operative Oxford hip and knee scores be used to predict patient satisfaction following joint replacement surgery and to guide patient selection?. The Journal of bone and joint surgery. British volume. 2011 Dec;93(12):1660-4.
4. Ikutomo H, Nagai K, Nakagawa N, Masuhara K. Falls in patients after total hip arthroplasty in Japan. J Orthop Sci. 2015 Mar 24
5 Timperley AJ, Biau D, Chew D, Whitehouse SL. Dislocation after total hip replacement – there is no such thing as a safe zone for socket placement with the posterior approach. Hip Int. 2016 Mar 23;26(2):121-7.
6 Tilbury C, Leichtenberg CS, Tordoir RL, et al. Return to work after total hip and knee arthroplasty: results from a clinical study. Rheumatology International. 2015;35(12):2059-2067. doi:10.1007/s00296-015-3311-4.
10 Lau RL, Perruccio AV, Evans HM, Mahomed SR, Mahomed NN, Gandhi R. Stem cell therapy for the treatment of early stage avascular necrosis of the femoral head: a systematic review. BMC Musculoskelet Disord. 2014 May 16;15:156. doi: 10.1186/1471-2474-15-156.

What does Darrow Stem Cell Institute research say about hip osteoarthritis and treatment with bone marrow derived stem cells? Four patients cases we published in the Clinical medicine insights. Case reports.

Clinical medicine insights. Case reports.

Watch the video.

The Vampire Facelift™ provides non-surgical solutions to the challenges of maintaining a youthful appearance in aging faces. The procedure addresses:

• Facial wrinkles
• Thinning skin
• Blotchy complexion
• Dull grey looking skin
• Loss of skin elasticity/sagging skin

It is called a Vampire Facelift™ because the facelift is achieved with the use of your own blood platelets combined with hyaluronic acids fillers. In this article we will concentrate on the blood portion.

The same PRP healing elements that we have written about throughout this website have been successfully applied to cosmetic medicine. The utilization of Platelets and other growth factors found in your blood, trigger new collagen production. This results is tauter, smoother and more youthful skin. When combined with dermal fillers; shape, color, texture and volume are all restored with the outcome lasting approximately 18 months.

In this article we will discuss how Platelet Rich Plasma, or “The Vampire Facelift,” can produce a more natural and youthful facial appearance than traditional surgical facelifts.

Although there can be a place for a surgical facelift, such procedures are not necessarily a panacea or cure-all to the concerns of the aging face. Cosmetic surgery when needed can remove excess skin and make the person appear younger. However, a surgical facelift can actually contribute to a face collapse as the skin stretches tighter against the bone making the person look skeletonized.

The Vampire Facelift provides non-surgical solutions to the challenges of maintaining a youthful appearance in aging faces. The procedure addresses:

• Facial wrinkles.
• Facial volume correction such as the thinning of the dermis (volume loss) seen with weight loss.
• Improve texture of the skin and rejuvenate the complexion by using the combination of Platelet Rich Plasma therapy (PRP) and dermal fillers.
• Changes in skin color. As we age we develop dull, greying skin because of reduced blood circulation in the face. The Vampire Facelift helps restore healthy natural looking glowing skin.
• The loss of skin elasticity.
• The slow collapse of the facial structure and subsequent droopiness in the shape of the face.

The PRP used in the Vampire Facelift® is the same as that used for years at Darrow Wellness to effectively speed joint, tendon and tissue repair. Our extensive experience using PRP to stimulate tissue repair and regeneration combined with our vast experience injecting fillers makes the Vampire Facelift® a cinch, with impressive results!

GROWTH FACTOR PRODUCTION KNOWN EFFECTS

• Epidermal Growth Factor (EGF) – Stimulates fibroblasts to secrete collagenase to degrade the matrix during the remodeling phase. Stimulates keratinocyte and fibroblast proliferation.
• Transforming Growth Factor- Promotes angiogenesis, up-regulates collagen production and inhibits degradation, promotes chemo attraction of inflammatory cells.
• Vascular Endothelial Growth Factor (VEGF) – Endothelial cells promote angiogenesis during tissue hypoxia.
• Fibroblast Growth Factor (FGF) – Promotes angiogenesis, granulation, and epithelialization via endothelial cell, fibroblast, and keratinocyte migration, respectively.
• Platelet-Derived Growth Factor (PDGF) – Attracts macrophages and fibroblasts to zone of injury. Promotes collagen and proteoglycan synthesis.
• Interleukins, Macrophages, keratinocytes, endothelial cells, lymphocytes, fibroblasts, osteoblasts, basophils, mast cells – Activates fibroblast differentiation. Induces collagen and proteoglycan synthesis.
• Colony Stimulating Factors – Stimulates granulocyte and macrophage proliferation.
• Keratinocyte Growth Factor – Fibroblasts stimulate keratinocyte migration, differentiation, and proliferation.

IN 2002, DOCTORS AT YALE UNIVERSITY DISCUSSED THE USE OF PRP FOLLOWING PLASTIC SURGERY.

• The response of living tissue to injury is a central component in the planning of all surgical procedures.
• The wound-healing process is typically divided into three phases (inflammatory, proliferative, and remodeling) and it is a complex process where many components interact to restore a wound defect.
• Platelets and their released growth factors are pivotal in the modulation of this entire process.
• Although several techniques may be used to achieve repair after initial injury, few initiate and actually accelerate tissue regeneration. Both platelet gel and fibrin glue (body glue) are effective hemostatic agents.
• Platelet gels, unlike fibrin glue, have a high concentration of platelets that release the bioactive proteins and growth factors necessary to initiate and accelerate tissue repair and regeneration.
• In particular, two growth factors that play a major role in platelet gels are platelet-derived growth factor and transforming growth factor beta, which significantly increases and stimulates the deposition of extracellular matrix (the “soup” that cartilage grows from).
• Platelet gels have global applications in surgery and are especially useful for the soft tissue and bony reconstructions encountered in facial plastic and reconstructive surgery. In these applications, their use has been associated with a decrease in operative time, necessity for drains and pressure dressings, and incidence of complications.1

This study followed similar research from doctors at Florida Atlantic University who tested “PRP” gel and fibrin glue to evaluate their effectiveness in stopping capillary bleeding in the surgical flaps of patients undergoing cosmetic surgery.

The types of surgical procedures included face lifts, breast augmentations, breast reductions, and neck lifts.

Capillary bed bleeding was present in all tested cases and effectively sealed within 3 minutes following the application of platelet gel and fibrin glue. 2 Clearly, PRP is a healer and has a place in cosmetic procedures.

REVERSING SUN DAMAGE

In 2003, doctors at Scripps-XIMED Medical Center began looking at growth factors in the repair of sun damaged skin. This is what they wrote:

• Though surgical procedures may be very effective, the associated healing time and potential risks have spurred the development of non-surgical treatments.
• There has also been an increasing depth of knowledge regarding wound healing and its control by growth factors as well as its modulation by the topical application of growth factors.

The objective of this study was to determine if the twice daily application of a combination of multiple growth factors (such as those found in PRP) to photodamaged facial skin results in any evidence of improvement after 60 days.

• Eleven of 14 patients showed clinical improvement in at least one facial area. The peri-orbital (around the eyes) region showed a statistically significant improvement.
• There was a decrease in the depth and number of textural irregularities or fine lines.
• Biopsies revealed new collagen formation  and thickening of the epidermis by 27%.
• Eight of 14 patients felt their wrinkles were improved, while 12 of 14 felt their skin texture was improved.

The application of a mixture of topical growth factors may stimulate the repair of facial photodamage resulting in new collagen formation, epidermal thickening and the clinical appearance of smoother skin with less visible wrinkling.3

SKIN NEEDLING

In this study, doctors from Turkey evaluated the efficacy and safety of intradermal injection of PRP in the human facial rejuvenation.

Twenty women ranging in age from 40 to 49 years were enrolled in the study. PRP increases dermal collagen levels not only by growth factors, but also by skin needling. PRP application could be considered as an effective (even a single application) and safety procedure for facial skin rejuvenation.4

A paper from China notes that needling can change the aging state of skin possibly by strengthening the activity of fibroblasts in the skin and by increasing the content of soluble collagen.8

CIRCULATION

In a 2012 paper from the New York Eye and Ear Infirmary’s department of plastic surgery. Doctors wrote how platelets created collagen, created a fat layer, and created circulation in skin. In this study:

Patients were injected with a Platelet-rich fibrin maxtrix in the deep dermis and immediate subdermis of the upper arms.

• Findings from examination supported the clinical observation of soft-tissue augmentation.
• As early as 7 days after treatment, activated fibroblasts (healing cells)  and new collagen deposition were noted and continued to be evident throughout the 10 week course of the study.
• Development of new blood vessels was noted by 19 days; also at this time, intradermal collections of adipocytes and stimulation of subdermal adipocytes were noted (fat layers of skin).5

NECK REVITALIZATION

In 2010, doctors in Italy wrote in the Journal of drugs and dermatology that “Face and neck revitalization with PRP is a promising easy-to-perform technique in face and neck rejuvenation and scar attenuation.”6

SAGGING SKIN

In 2014, doctors in Turkey wrote that in their patient studies, there was statistically significant difference regarding the general appearance, skin firmness-sagging and wrinkle state of the patients before and after three PRP applications.7

What is Platelet Rich Plasma?

The term “Platelet Rich Plasma,” is routinely used to describe the healing injectable solution made from a concentration of a patient’s blood platelets.

Blood platelets contain many healing factors. When the platelets are separated from the whole blood, an injectable  “platelet rich plasma,” (PRP) healing solution is created. A solution rich in powerful facial rejuvenation growth factors.

Here is a brief introduction to the growth factors of your blood platelets and what scientists have found them to be able to do in the skin rejuvenation process.

• Epidermal Growth Factor (EGF) – EGF stimulates the epidermis, the outer skin layers,  to create new skin. It does so by sending chemical messages to get rid of old skin and signals to cells that create new skin to start the skin remodeling phase of healing.
• Transforming Growth Factor (TGF) – TGF promotes angiogenesis, the creation of new blood vessels which brings fresh circulation to the skin. Through chemical signalling TGF stimulates collagen production and pro-inflammatory healing cells.
• Vascular Endothelial Growth Factor (VEGF) – VEGF brings oxygen, the great healer, to damaged skin. It does so by recognizing when tissues are oxygen starved, and are having difficulty “breathing,” this is called tissue hypoxia.
• Fibroblast Growth Factor (FGF) – FGF through chemical signalling brings blood to damaged skin cells and organizes the immune cells to move towards the damaged skin to remove and place dead skin cells.
• Platelet-Derived Growth Factor (PDGF) – PDGF sends chemical signals to macrophages (cells that remove dead dying tissue) and fibroblasts (cells that promote collagen healing) to damaged skin areas. PDGF promotes collagen and proteoglycan (the proteins of connective tissue – elasticity) synthesis.
• Colony Stimulating Factors – (CSF) are fascinating growth factors. They send signals to resident stem cells to change themselves into the components necessary to basically “fill in the cracks.” If skin is short on collagen, the stem cells turn themselves into collagen. If healing factors such as  granulocytes (wound healers) are in short supply, they turn themselves into that. This is called stem cell differential. Stem cell differential is at the heart of the emergence of stem cell therapy discussed throughout this website.
• Keratinocyte Growth Factor (KGF) – Keratinocytes are epidermal cells that represent 90% of the make up the epidermis.  KGF stimulates Keratinocyte production, new skin.

It is truly amazing what a drop of blood can do. In the hands of an expert clinician it can transform the appearance of tired, aged skin into a more youthful and vibrant facial appearance.

Can blood really do all this?

Every skin product, whether the Vampire Facelift, traditional surgical facelift, creams, lotions or other injections such as botox, have before and after pictures. They all show improvements.  But why do we think the Vampire Facelift is the treatment to offer? Science. PRP has shown long-term to be able to change the skin of the face on a cellular level to that of a more youthful appearance.

The science is very deep.

2017: A study from leading Italian dermatology researchers found PRP treatments provided significant clinical improvement in skin texture, elasticity, skin smoothness parameters, and skin barrier function (keeping moisture in).1

A 2016 study in the Journal of Cosmetic Dermatology recorded:

• A series of 94 female patients with varying degrees of facial aging signs were treated with PRP and hyaluronic acid.
• Average age was 53, youngest being 48, oldest 63. Average number of injections were about 3 and one-half.

Patients were asked to rate their personal satisfaction with their skin texture, pigmentation, and sagging. In addition, the overall results were rated by three independent physicians and the patients themselves. The outcomes were peer-reviewed, and correlations between the degree of the aesthetic scores and the number of injections were explored.

• There was a statistically significant difference in general appearance, skin firmness-sagging and skin texture according to the patients’ before and after applications of PRP.
• A statistically significant correlation was found between the number of injections and overall satisfaction.2

A new paper from doctors in Turkey suggests that Platelet Rich Plasma Therapy (PRP) can give you a younger looking neck and face.

Published in the prestigious medical journal Annals of Dermatology,  the doctors gave only one treatment of PRP vampire facelift. These photos are of patients treated during the study:

1 Cameli N, Mariano M, Cordone I, Abril E, Masi S, Foddai ML. Autologous Pure Platelet-Rich Plasma Dermal Injections for Facial Skin Rejuvenation: Clinical, Instrumental, and Flow Cytometry Assessment. Dermatol Surg. 2017 Apr 3.

2 Ulusal BG. Platelet-rich plasma and hyaluronic acid – an efficient biostimulation method for face rejuvenation. J Cosmet Dermatol. 2016 Sep 5. doi: 10.1111/jocd.12271.

The Vampire Facelift™ provides non-surgical solutions to the challenges of maintaining a youthful appearance in aging faces. The procedure addresses:

• Facial wrinkles
• Thinning skin
• Blotchy complexion
• Dull grey looking skin
• Loss of skin elasticity/sagging skin

It is called a Vampire Facelift™ because the facelift is achieved with the use of your own blood platelets combined with hyaluronic acids fillers. In this article we will concentrate on the blood portion.

The same PRP healing elements that we have written about throughout this website have been successfully applied to cosmetic medicine. The utilization of Platelets and other growth factors found in your blood, trigger new collagen production. This results is tauter, smoother and more youthful skin. When combined with dermal fillers; shape, color, texture and volume are all restored with the outcome lasting approximately 18 months.

In this article we will discuss how Platelet Rich Plasma, or “The Vampire Facelift,” can produce a more natural and youthful facial appearance than traditional surgical facelifts.

Although there can be a place for a surgical facelift, such procedures are not necessarily a panacea or cure-all to the concerns of the aging face. Cosmetic surgery when needed can remove excess skin and make the person appear younger. However, a surgical facelift can actually contribute to a face collapse as the skin stretches tighter against the bone making the person look skeletonized.

The Vampire Facelift provides non-surgical solutions to the challenges of maintaining a youthful appearance in aging faces. The procedure addresses:

• Facial wrinkles.
• Facial volume correction such as the thinning of the dermis (volume loss) seen with weight loss.
• Improve texture of the skin and rejuvenate the complexion by using the combination of Platelet Rich Plasma therapy (PRP) and dermal fillers.
• Changes in skin color. As we age we develop dull, greying skin because of reduced blood circulation in the face. The Vampire Facelift helps restore healthy natural looking glowing skin.
• The loss of skin elasticity.
• The slow collapse of the facial structure and subsequent droopiness in the shape of the face.

The PRP used in the Vampire Facelift® is the same as that used for years at Darrow Wellness to effectively speed joint, tendon and tissue repair. Our extensive experience using PRP to stimulate tissue repair and regeneration combined with our vast experience injecting fillers makes the Vampire Facelift® a cinch, with impressive results!

GROWTH FACTOR PRODUCTION KNOWN EFFECTS

• Epidermal Growth Factor (EGF) – Stimulates fibroblasts to secrete collagenase to degrade the matrix during the remodeling phase. Stimulates keratinocyte and fibroblast proliferation.
• Transforming Growth Factor- Promotes angiogenesis, up-regulates collagen production and inhibits degradation, promotes chemo attraction of inflammatory cells.
• Vascular Endothelial Growth Factor (VEGF) – Endothelial cells promote angiogenesis during tissue hypoxia.
• Fibroblast Growth Factor (FGF) – Promotes angiogenesis, granulation, and epithelialization via endothelial cell, fibroblast, and keratinocyte migration, respectively.
• Platelet-Derived Growth Factor (PDGF) – Attracts macrophages and fibroblasts to zone of injury. Promotes collagen and proteoglycan synthesis.
• Interleukins, Macrophages, keratinocytes, endothelial cells, lymphocytes, fibroblasts, osteoblasts, basophils, mast cells – Activates fibroblast differentiation. Induces collagen and proteoglycan synthesis.
• Colony Stimulating Factors – Stimulates granulocyte and macrophage proliferation.
• Keratinocyte Growth Factor – Fibroblasts stimulate keratinocyte migration, differentiation, and proliferation.

IN 2002, DOCTORS AT YALE UNIVERSITY DISCUSSED THE USE OF PRP FOLLOWING PLASTIC SURGERY.

• The response of living tissue to injury is a central component in the planning of all surgical procedures.
• The wound-healing process is typically divided into three phases (inflammatory, proliferative, and remodeling) and it is a complex process where many components interact to restore a wound defect.
• Platelets and their released growth factors are pivotal in the modulation of this entire process.
• Although several techniques may be used to achieve repair after initial injury, few initiate and actually accelerate tissue regeneration. Both platelet gel and fibrin glue (body glue) are effective hemostatic agents.
• Platelet gels, unlike fibrin glue, have a high concentration of platelets that release the bioactive proteins and growth factors necessary to initiate and accelerate tissue repair and regeneration.
• In particular, two growth factors that play a major role in platelet gels are platelet-derived growth factor and transforming growth factor beta, which significantly increases and stimulates the deposition of extracellular matrix (the “soup” that cartilage grows from).
• Platelet gels have global applications in surgery and are especially useful for the soft tissue and bony reconstructions encountered in facial plastic and reconstructive surgery. In these applications, their use has been associated with a decrease in operative time, necessity for drains and pressure dressings, and incidence of complications.1

This study followed similar research from doctors at Florida Atlantic University who tested “PRP” gel and fibrin glue to evaluate their effectiveness in stopping capillary bleeding in the surgical flaps of patients undergoing cosmetic surgery.

The types of surgical procedures included face lifts, breast augmentations, breast reductions, and neck lifts.

Capillary bed bleeding was present in all tested cases and effectively sealed within 3 minutes following the application of platelet gel and fibrin glue. 2 Clearly, PRP is a healer and has a place in cosmetic procedures.

REVERSING SUN DAMAGE

In 2003, doctors at Scripps-XIMED Medical Center began looking at growth factors in the repair of sun damaged skin. This is what they wrote:

• Though surgical procedures may be very effective, the associated healing time and potential risks have spurred the development of non-surgical treatments.
• There has also been an increasing depth of knowledge regarding wound healing and its control by growth factors as well as its modulation by the topical application of growth factors.

The objective of this study was to determine if the twice daily application of a combination of multiple growth factors (such as those found in PRP) to photodamaged facial skin results in any evidence of improvement after 60 days.

• Eleven of 14 patients showed clinical improvement in at least one facial area. The peri-orbital (around the eyes) region showed a statistically significant improvement.
• There was a decrease in the depth and number of textural irregularities or fine lines.
• Biopsies revealed new collagen formation  and thickening of the epidermis by 27%.
• Eight of 14 patients felt their wrinkles were improved, while 12 of 14 felt their skin texture was improved.

The application of a mixture of topical growth factors may stimulate the repair of facial photodamage resulting in new collagen formation, epidermal thickening and the clinical appearance of smoother skin with less visible wrinkling.3

SKIN NEEDLING

In this study, doctors from Turkey evaluated the efficacy and safety of intradermal injection of PRP in the human facial rejuvenation.

Twenty women ranging in age from 40 to 49 years were enrolled in the study. PRP increases dermal collagen levels not only by growth factors, but also by skin needling. PRP application could be considered as an effective (even a single application) and safety procedure for facial skin rejuvenation.4

A paper from China notes that needling can change the aging state of skin possibly by strengthening the activity of fibroblasts in the skin and by increasing the content of soluble collagen.8

CIRCULATION

In a 2012 paper from the New York Eye and Ear Infirmary’s department of plastic surgery. Doctors wrote how platelets created collagen, created a fat layer, and created circulation in skin. In this study:

Patients were injected with a Platelet-rich fibrin maxtrix in the deep dermis and immediate subdermis of the upper arms.

• Findings from examination supported the clinical observation of soft-tissue augmentation.
• As early as 7 days after treatment, activated fibroblasts (healing cells)  and new collagen deposition were noted and continued to be evident throughout the 10 week course of the study.
• Development of new blood vessels was noted by 19 days; also at this time, intradermal collections of adipocytes and stimulation of subdermal adipocytes were noted (fat layers of skin).5

NECK REVITALIZATION

In 2010, doctors in Italy wrote in the Journal of drugs and dermatology that “Face and neck revitalization with PRP is a promising easy-to-perform technique in face and neck rejuvenation and scar attenuation.”6

SAGGING SKIN

In 2014, doctors in Turkey wrote that in their patient studies, there was statistically significant difference regarding the general appearance, skin firmness-sagging and wrinkle state of the patients before and after three PRP applications.7