Marc Darrow MD, JD. Thank you for reading my article. You can ask me your questions about bone marrow derived stem cells using the contact form below. 

Before we begin this article, please understand:

Stem cell and PRP injections for musculoskeletal conditions are NOT FDA APPROVED. While research has shown that stem cell and PRP therapy may offer benefits to patients with orthopedic issues, many of these same studies conclude that further evaluation is needed from large, well-controlled clinical trials to verify possible benefits. We only treat orthopedic issues. We do not treat disease. We do not offer IV treatments.

We do not promise stem cell or PRP therapy as a cure for any condition. We provide stem cell and PRP therapy as a same day procedure, without manipulation, stimulation, or culturing of cells. Stem Cell and PRP therapy does not work for everyone. Results achieved by some patients may not be typical for other patients. There are no guarantees that this treatment will help you. All information on this website including reference to current research journals is for educational purposes only. There is controversy in the medical community about whether umbilical cord blood stem cells are alive or dead. You are encouraged to speak with your private medical doctor to help you decide if our treatments might be beneficial for you.

Everyday we get many emails. Some of these emails concern neck pain. In many of these emails the person asking a question, sends me their cervical neck MRI findings. That is all they send. A cut and past of their MRI report.They never say what their pain is like, how this neck pain is affecting their day to day quality of life, or any other glimpses into how this chronic neck pain is hurting them. The email is all about the MRI. Our own clinical findings and that of researchers is that maybe your neck pain should not be all about your MRI.

As many of you are already aware, MRI interpretations can be a long, hard to understand, somewhat frustrating thing for a patient to see and read. The MRI may also seemingly describe a lot of problems with a lot of terminology that can be considered frightening. This may, for many, cause unneeded anxiety and fear. I have been doing regenerative medicine for more than 20 years. Over the years we have been blessed to have helped many people with their neck pain. I have seen patients with varying degrees of degenerative cervical spine disease trying to avoid surgery, I have also seen patients after a cervical neck surgery with more challenges than before the surgery who, unfortunately, may have had a surgery that they did not need. The one thing many of these people had in common was a cervical neck MRI that suggested a lot more problems than the patient was actually having.

Is the neck MRI really showing what my problem is?

Interpreting MRIs can be challenging. In a new study, (1) researchers found the most prevalent MRI findings were:

  • Cervical foraminal stenosis (77%)
    • The foramen is the gap or passages between the vertebrae that the nerves pass through. If this passageway is made narrower by bony overgrowth there is obviously less space for the nerves to pass through. Over time this passageway can close up enough that the nerves are “pinched.” Why does the bone overgrow? Bone overgrowth can be caused by spinal instability. When the cervical spine is unstable, loose, or wobbly, neck moves in an unnatural motion. Cervical neck instability is generally caused by stressed, weakened and damaged spinal ligaments.

As bad as it may look on an MRI, cervical foraminal stenosis, may not be causing the patient any problems: We have seen this clinically and researchers have seen it and reported it in their published studies:

In the Clinics in orthopedic surgery, (2) surgeons wrote: “Cervical foraminal stenosis is one of the degenerative changes of the cervical spine; however, correlations between the severity of stenosis and that of symptoms are not consistent in the literature. Studies to date on the prevalence of stenosis are based on images obtained from the departments treating cervical lesions, and thus patient selection bias may have occurred.”

The surgeons suggested that the patient was treated based on what the MRI said, not what they patient said was wrong with them. Perhaps this is why when people send me an email, some never suggest what their symptoms are, only what their MRI said. In this study, the surgeons also suggest that patients may have been sent to surgery that was suggested based on the bias of the MRI interpretation. A surgery the patient may have not needed at all.

Returning to our initial overview of most prominent MRI readings, next came

  • uncovertebral arthrosis (74%)
    • This is wear and tear damage occurring at the uncovertebral joint or Luschka’s joint, located on each side of the four cervical vertebrae at C3 to C7 in the cervical spine. This is where  bone spurs most commonly develop.
  • and disc degeneration (67%)
    • This is of course are the problems herniated or pinched nerves.

Do these problems indicate surgery? Research: “It is difficult to rule out the possibility of bias; radiological findings may influence surgeon’s decision making.”

Let’s look again at the study in the Clinics in orthopedic surgery. 

  • “Cervical neuromuscular disease is manifested by symptoms in specific neuromuscular regions of the upper limbs, and radiating pain is mostly caused by cervical nerve root compression due to stenosis of the cervical vertebrae. In the presence of progressive neurological deterioration, intractable pain, signs of myelopathy, fracture, instability, or ligamentous injury, and bone anomalies or destruction are associated with surgical indications.
  • “However, (this can all be) asymptomatic. To determine the affected level that requires cervical spine surgery, the patients undergo neurological and physical examinations and then both CT and magnetic resonance imaging (MRI); if the results do not match, additional neurophysiological testing is required to determine the affected level. However, if neurological examinations are performed after radiological examinations, it is difficult to rule out the possibility of bias; radiological findings may influence surgeon’s decision making.”

Sometimes surgery is recommended. But should it be for you?

This is a good question and one that certainly needs to be answered inside an examination room. However, returning to our initial overview of the most prominent MRI readings, let’s look at the least prevalent finding:

  • nerve root compromise or compression (2%)

Now if you are in that 2% there is a strong chance that you are suffering from cervical radiculopathy or pain from the nerves. In theses cases surgical options may have to be considered, but, a second opinion looking for non-surgical options may also be warranted.

In my article on this website: Why do patients rush to cervical neck surgery? Fear of disability? Fear of opioid addiction? I write that I regularly see patients who have been told by another doctor that they need a neck surgery to prevent the further degeneration of their cervical spine. Some of these patients are very frightened by what their doctor told them. Some were told that if their symptoms progress they could risk permanent damage to their ability to function maybe to the point of paralysis. I show that research has strongly suggested that many patients decide on cervical fusion surgery because they fear a progression of their problem that will lead to permanent disability. However, follow-up data on patients with degenerative disease of the upper (cervical) spinal vertebrae show little or no evidence of worsening degeneration over time.

Treating cervical ligaments to restore neck stability

In our office, treating chronic neck pain begins with the repair and strengthening of cervical ligaments. Ligaments are the connective tissue that hold your cervical spine vertebrae in place and your neck in its correct anatomical alignment. When your ligaments are weak, they can no longer hold the neck in proper alignment. When the neck is not in alignment the vertebrae can pinch nerves, constrict arteries, put pressure on your esophagus among other problems that may cause the myriad of symptoms.

Our treatments to restore cervical neck stability by repairing and regenerating the neck ligaments

Platelet Rich Plasma injections

PRP treatments involve collecting a small amount of your blood and spinning it in a centrifuge to separate the platelets from the red cells. The collected platelets are then injected back into the injured area to stimulate healing and regeneration. Research has shown PRP to be effective in treating degenerative disc disease by addressing the problems of cervical spine ligament instability.

Stem cell injections

Stem cell injections involve the use of Bone Marrow derived stem cells or Umbilical Cord Blood stem cells.The stem cell treatments help restore ligaments strength by causing the regeneration of ligament, tendon, cartilage and bone regeneration.

Do you have questions? Ask Dr. Darrow

A leading provider of stem cell therapy, platelet rich plasma and prolotherapy

PHONE: (800) 300-9300 or 310-231-7000

There is controversy in the medical community about umbilical cord blood stem cells. Some insist that the injectable solution contains abundant live umbilical cord blood stem cells. Some suggest that the stem cells are not alive. Some research shows that stem cells may release cytokines and growth factors that awaken native stem cells. We also use PRP and bone marrow depending on the patient’s pathology and requirements. We are in the process of doing a large study on cord blood stem cells to ascertain which treatments are the most successful. Short term results show cord blood stem cells and bone marrow concentrate to be statistically equal in efficacy on the scales we record..

1 Jensen RK, Jensen TS, Grøn S, Frafjord E, Bundgaard U, Damsgaard AL, Mathiasen JM, Kjaer P. Prevalence of MRI findings in the cervical spine in patients with persistent neck pain based on quantification of narrative MRI reports. Chiropractic & manual therapies. 2019 Dec;27(1):13.

2 Ko S, Choi W, Lee J. The Prevalence of Cervical Foraminal Stenosis on Computed Tomography of a Selected Community-Based Korean Population. Clin Orthop Surg. 2018 Dec;10(4):433-438. doi: 10.4055/cios.2018.10.4.433. Epub 2018 Nov 21.